Autoimmune Disease IX Crohn’s Disease, Ulcerative Colitis (Inflammatory Bowel Disease IBD)

By on May 1st, 2018 in Articles, Autoimmune Disease


Introduction

In this article we shall describe Inflammatory Bowel diseases, Crohn’s and Ulcerative colitis and not be confused with Irritable Bowel Syndrome (IBS).  There was a time that all these conditions were defined as Functional bowel diseases, but IBS, also referred to as ‘spastic colon’,although expresses similar symptoms, it is less severe than IBD since it does not cause tissue damage.

What are these conditions

Inflammatory Bowel Disease (IBD) is a term used to define conditions like Crohn’s Disease, and Ulcerative colitis because they both define disorders that cause chronic inflammation of the digestive tract and the colon. Crohn’s disease causes inflammation of the digestive tract epithelium characterized by ‘skipped lesions’ throughout the length of the small intestine, while Ulcerative colitis also causes inflammation but  in the large intestine ( colon ) and rectum. This is shown in the diagrams below. Although in Crohn’s disease as it is generally the ileocecal area/cecum of the large intestine that becomes inflammed, but it can also affect the rectal area as well, and inflammation can spread to other parts of the colon ( referred to as Crohn’s colitis). While in Ulcerative Colitis, the inflammation can also spread from the sigmoid colon/rectal area to any part of the colon.

Crohn’s Disease

This type of IBD cause deep tissue inflammatory damage where it can also block the intestine from scar tissue.  The typical symptoms include abdominal pain, diarrhea, rectal bleeding, loss of appetite/weight loss, as well the formation of sores, or ulcers that break through into the surrounding tissue.  The conventional medical community are puzzled when faced with IBD’s because they are sometimes intermittent, occurring every few months or years, and there have been cases where symptoms appear once or twice and disappear never to return.  Well maybe if the body is given a chance to heal itself without it being suppressed by prescribed chemicals. Conventional medicine are resigned to the fact that they can’t fix it, so in their opinion it’s incurable and victims will have to limp, wounded through life knowing that their risk of getting cancer has just risen 20 times.  The body is self healing..what do you mean it’s incurable ??.

Recent research Research Uncovers Bacteria Linking Crohn’s Disease to Arthritis

A recent study in 2017 headed by conventional medical detective Dr Randy Longman and other scientists, from the Jill Roberts center for Inflammatory Bowel disease at the New York Presbyterian and Weill Cornell Medicine, examined fecal samples from various IBD patients. What they found was an abundance of E-Coli bacteria coated with infection fighting antibodies immunoglobulin-A (IgA). These patients were also suffering from a condition called spondyloarthritis, an inflammatory condition that affects the joints and entheses (locations where ligaments and tendons attach to the bones), and comes in various flavors ‘Ankylosing spondylitis, reactive arthritis and psoriatic arthritis. So the medical detectives were able to link these IgA antibodies to the T cells TH17, which in turn was activated by IL 23. Dr Simpson professor of small animal medicine at Cornell’s College of Veterinary Medicine who mentioned sequencing the gut flora said:

“We knew there was smoke but we didn’t know where the fire was,” said Dr. Simpson, who added that each collaborator provided unique expertise to uncover the findings.  “If we can block the ability of bacteria to induce inflammation, we may be able to kick Crohn’s disease and spondyloarthritis into remission.”

This is a another example of scientists looking down a rabbit hole searching for answers when the answer is staring them in the face…if we can block the ability of the bacteria to induce inflammation ???…but isn’t this what allopathic medicine do all the time..they are called antibiotics.  Why do you think they found E-Coli in the fecal samples…?..because the gut is unbalanced releasing an overgrown colony of pathogenic flora; in this case E.Coli and the immune system is trying to eliminate it. Why didn’t they look in the lymphatics..see what’s hiding in there.

Crohn’s disease breakthrough

In may 2017 a lawyer who had been suffering from Crohn’s disease for 16 years said :

“I was diagnosed with Crohn’s disease   about 16 years ago, after having severe intestinal pain, nausea, trouble eating and sleeping. I tried all other conventional treatments available, from remicade and steroids to biologics and all other immunosuppressants. I had side effects ranging from dangerous allergic reactions to liver failure. I was in severe chronic pain 24/7 and needed to rely on opiates just to be able to eat one meal per day. After an emergency surgery last year which resulted in the removal of over one foot of my intestine, the symptoms of Crohn’s disease came back to affect an even larger amount of my small intestine. I was told that my options were limited to going back on the same unsuccessful medications, or risk having additional surgeries. In the interim, my health had deteriorated to the point that I was forced to resign from job in my 5th year practicing law due to multiple and repeated hospitalizations.”

He then received a new therapy called IV Ketamine infusion therapy which gave him much relief as he stated, but Ketamine is a drug used for surgical anesthesia and a powerful painkiller, and unless I am mistaken it doesn’t fix anything, but simply brings pain relief like any opioid would. Heal the cause ( stress. toxicity and/or poisoned food) and the body will eventually return to normal.

Crohn’s and Colitis Canada website:

The following statements are written on this site:

ARE YOU AT RISK?

Currently, scientists believe that a genetic tendency and a trigger in the environment are combined to set off inflammation in the gut. Instead of being dampened down, the immune system then continues to run amok. The chronic (lifelong) process that results can manifest as either Crohn’s disease or ulcerative colitis.

One thing we do know – YOU did not cause your disease by something you did or didn’t do. It wasn’t your diet or the stress in your life that brought this on, so free yourself (and anyone else!) from guilt over the cause of Crohn’s disease or ulcerative colitis.

I’m sorry but the last paragraph is simply not true, diet and/or stress is exactly what causes the problem.  I say it again, the only genetic component is an inherited unhealthy gut, or it was made so from either chemical, physical or emotional stressors The trigger in the environment could be toxicity and definitely nutrient deficiency, poisonous food, and/or STRESS.

Conventional Medicine’s Dark Age treatment

The medical community still use expensive diagnostic procedures such as Ileocolonoscopy to examine the small intestine to verify a diagnosis of either Crohn’s disease ( Inflammatory bowel syndrome (IBD)) or Ulcerative Colitis (UC).  Their observance of granular and brittle mucosa and in some cases deep erosions of the mucosa, chronically inflamed, and possibly serpiginous ulcers, polyps suggest a UC diagnosis. This endoscopic procedure is used to diagnose IBD or Crohn’s disease. If conventional medicine deem it necessary, they will use a barbaric procedure to actually remove part of the small intestine referred to as Ileocolic resection (shown in the diagrams above as the Ileocolic junction) involving the removal of the end of the small intestine (ileum ),  the start of the ascending part of the large intestine and the cecum pouch…WHY ??, because they can’t fix, it so its removed to provide symptomatic relief. In one 2014 study they state :

‘Despite the frequency of these procedures, a significant knowledge gap remains in describing the inherent effects of intestinal resection on host physiology and disease pathophysiology’

Another study states :

Crohn’s disease (CD) is a chronic inflammatory bowel disease that can involve any segment of the gastrointestinal tract. Despite the increasing use of immunosuppressive drugs, up to 70% of patients will undergo surgical resection during the course of their disease.  After ileocolonic resection, despite removal of all macroscopic lesions, the disease typically recurs at the site of resection and extends to the neoterminal ileum following the same pattern as initially.

So what this means is that having undergone this barbaric procedure and putting your health at further risk by taking drugs that paralyse the immune system, they state ‘the disease typically recurs at the site of resection…following the same initial pattern’.   What did the lawyer say after his emergency surgery ?….After an emergency surgery last year which resulted in the removal of over one foot of my intestine, the symptoms of Crohn’s disease came back to affect an even larger amount of my small intestine…do you want to know why!!..because the underlying cause was never diagnosed, so surgery was approved based on symptoms.  People, you have to be more aware of how your body works and realise that removing parts of the body has consequences, especially when the medical profession know that this is futile procedure, since it does nothing, except possibly bring some temporary relief.  All that had to be done was to remove the cause in the first place which was probably stress and poisonous food and fix the imbalance in the gut

Other studies have explored the cause and actually uncovered the cause but it eluded them:

‘Although the exact etiology remains unknown, it is a complex interaction between genetic predisposition, environmental risk factors and immune dysregulation to intestinal microbiota’

Crohn’s disease (CD), ulcerative colitis (UC), and pouchitis appear to be caused by pathogenic T-cell responses to discrete antigens from the complex luminal microbiota, with susceptibility conferred by genetic polymorphisms that regulate bacterial killing, mucosal barrier function, or immune responses. Environmental triggers initiate or reactivate inflammation and modulate genetic susceptibility. New pathogenesis concepts include defective bacterial killing by innate immune cells in CD, colonization of the ileum in CD with functionally abnormal Escherichia coli that adhere to and invade epithelial cells and resist bacterial killing, and alterations in enteric microbiota composition in CD, UC, and pouchitis detected by molecular probes. The considerable therapeutic potential of manipulating the enteric microbiota in inflammatory bowel disease patients has not been realized, probably due to failure to recognize heterogeneous disease mechanisms that require individualized use of antibiotics, probiotics, prebiotics, combination therapies, and genetically engineered bacteria to restore mucosal homeostasis.

They found the answer by stating that

‘The considerable therapeutic potential of manipulating the enteric microbiota in inflammatory bowel disease patients has not been realized, probably due to failure to recognize heterogeneous disease mechanisms that require individualized use of antibiotics, probiotics, prebiotics, combination therapies, and genetically engineered bacteria to restore mucosal homeostasis.’ ( except for the antibiotics and GMO Bacteria)

The best feeling, is being the best version of yourself

A young man in his twenties receives a diagnosis of ulcerative colitis after a colonoscopy exam while working a stressful job working 60 hours/week. He began taking prescription drugs including prednisone, Asacol, and Lialda. At the age of 24, he replaced his high pressure job for one that had different stressful conditions, and then suddenly he crashed, couldn’t eat and lost 40 pounds and continued with more drugs including immunomodulators, immunosuppressants, Entyvio, Remicade, 6MP, methotrexate. After 3 years of taking these drugs he always felt tired and more sick.  His physicians were scratching their heads * and then suggested he install a Colostomy bag**. At this point he started to re evaluate what was going on and he did read a book called ‘Patient heal thyself which helped, but 2 years down the road still trying to deal with the stressors in his life he became very sick again.  He spent 7 weeks in the hospital where doctors prescribed Chemotherapy because they thought he a had a virus. He was prescribed 4 antibiotics and 200mg of Prednisone because he could not eat anymore, so food was delivered intravenously, and to kill the pain they prescribed 3 grams of Dilaudid, a very powerful, very addictive opioid, and still he didn’t improve. The doctors then suggested to start cutting and remove the offending organ, the large intestine or part of it.  Eventually, he escaped and got treatment by a naturopath.

I hope that from this true story, if you do receive a diagnosis of any of these inflammatory conditions you run as fast as you can from conventional medicine and get the first bus out of town, and get as far away as possible from any clinic or hospital.  

Hopefully this true story causes you to think twice about blindly following the advise of your doctor.  If you do receive a diagnosis of any of these inflammatory conditions, please consider getting a second opinion.  What was he prescribed..Prednisone (synthetic corticosteroid drug that paralyses the immune system). Asacol ( Anti-inflammatory drug), lialda ( Anti-inflammatory drug ), Entyvio (  A biological response modifier drug that is supposed to boost the immune system to improve its function), Remicade ( described as a ‘chimeric monoclonal antibody biologic’ that paralyses tumor necrosis factor alpha cytokine used by the immune system to assist in an inflammatory response), 6MP ( Used in cancer treatment it inhibits the metabolism of Purines which are biologically synthesised as Nucleotides which are the building blocks of DNA and RNA), Methotrexate ( another cancer/chemo poison that inhibits DNA.RNA synthesis), Dilaudid ( a powerful opium based opioid pain killer).  What a list..that’s why they painted the skull and crossbones on his room at the hospital and nurses had to wear hazmat suits.  I have only questions..why was he given 2 anti-inflammatory drugs. Why was he given an immune system booster at the same time as given a 1 drug that paralyses part of the inflammatory response of the immune system ( TNF-Alpha), and another drug Prednisone that paralyses the immune system per se. Why was he given 2 drugs that interfere with DNA/RNA synthesis. It is of interest that the 6MP drug development was initiated by Cornelius Rhoads who ran the chemical weapons program for the US army leading to the discovery that nitrogen mustards could be used to fight cancer.  If these doctors were engineers nothing would work, we would still be travelling in handsome cabs, horse drawn buggies and if we were really lucky typewriters.

* Did I ever tell you about Reggie Lewis aged 28 captain of the Boston Celtics Basketball team. According to Dr Wallach in 1993 Reg Lewis suffered hypertrophic cardiomyopathy, while playing an off season practice game on July 23 1993.  They managed to revive him and take him to Hospital where a Dr Nestor  and a team of cardiologists were trying to figure the best course of treatment and came up with the idea of a heart transplant which would be great publicity “Basketball star playing again after successful heart transplant operation” While they were contemplating their own ego boost, Lewis went into cardiac arrest and died 3 weeks after the last incident. Dr Wallach and his wife, also a doctor,  in 1990 reviewed 1700 autopsy cases of keshan’s disease in Chinese children under 10 years of age where 595 displayed classic pancreatic,liver,heart and lung problems associated with cystic fibrosis, but all of them showed classic lesions associated with hypertrophic cardiomyopathy ( where the heart muscle, the myocardium thickens ( hypertrophied) making the heart work harder to pump)  and muscular dystrophy. As a result of a large study that lasted for 3 years Wallach et al concluded that all 3 conditions were a result of selenium deficiency. Ironically, Dr Nestor 1 ½ years later at the age of 48 died of the same condition in Dedham Massachusetts. Wikipedia tells a different story..so who knows. Take home message;  Selenium is vital to your health as discussed in the article series ‘90 essential nutrients’. This is just another example of the futility of modern medicine, contemplating heart transplants when all that was needed was a handful of selenium rich brazil nuts that would have eventualluy cured him

** yet another invention from the annals of ‘dark age era’ medicine that entails a colonic bypass mechanism allowing the colon to heal ( which of course it won’t, because you haven’t eliminated the reason it was damaged in the first place). This barbaric surgery diverts one end of the large intestine ( the colon) into a visible opening (stoma) where they attach the.Colostomy bag.  I suppose one thing to consider is, that, if any of these ‘doctors’ get struck off for malpractice they can always get a job as plumbing consultants, so if their design goes south we only have to worry about a flooded bathroom for example as opposed to putting lives at risk.

Stress causes gut dysbiosis

Let us discuss stress, since this must take centre stage in terms of causality for most of these conditions.  We must also, within the same context, talk about the Gut-brain axis. Two of the top destroyers pf microbiota balance is antibiotics and stress. I have always advocated that if you are foolish enough…excuse me…talked into taking antibiotics, at least take some probiotics on alternate days to counteract the destruction (even Alexander Fleming, the inventor of antibiotics suggested this). Stress encompasses all 3 stressors due to the gut-brain connection, such as butterflies in the stomach from conscious anxiety to taking prescription poisons to treat abnormal gut reactions and abnormal bowel habits brought on by a stressful lifestyle. Signals in the upper and lower regions of the GI tract can be synchronous or asynchronous depending on the emotion, e.g Fear causes both regions to go in opposite directions (asynchronous) while Anger upregulates and cause both signals to travel in the same direction ( synchronous).  To put it in the words of Emeran Mayer MD ( The Mind-Gut connection)

“ the gut is the theatre in which the drama of emotion is played”

An abnormal consequence of stress can trigger a condition called ‘Cyclical Vomiting Syndrome’ where the sufferer experiences severe abdominal pain followed by unstoppable vomiting, that cause the majority of gastroenterologists to scratch their heads in perplexity.  This condition is a gut reaction triggered by a constantly primed signal along the HPA axis possibly the Corticotropin Release Factor (CRH) signal sent from the Hypothalamus to the pituitary gland, or the Adrenocorticotropic Hormone (ACTH) that activates the adrenal glands. As a result of a stress event it triggers the already primed axis, switching the body into stress mode lighting up every organ and cell in the body.

Gut-Brain axis

In my articles on the microbiome, I wrote that stress is another significant factor that can reshape the microbiome, coupled with an increase in gut barrier permeability, and a definite role in barrier dysfunction. As I stated above, under stress, the release of the CRF  hormone causes gut barrier distress. There are many studies highlighting Gut microbiome shifts in patients suffering from Irritable Bowel syndrome (IBS) such as an altered Firmicutes/Bacteroidetes ratio as well as psychiatric symptoms such as depression and anxiety, confirming the interactivity of the gut brain axis.

This crucial link between our microbiome and the brain is bi-directional insofar as the brain influences the on-going development of our microbial colonies, while our microbial colonies manufacture neuroactive substances that include neurotransmitters ( serotonin ) and metabolites that influence the brain. Our microbiome use the Vagus nerve *** ( this is the longest cranial nerve that connects the medulla oblongata just under the brain to the large intestine, the colon ) to communicate with the brain, while the metabolites secreted from our microbes influence the host immune system which maintains its own independent connection to the brain.

*** The Vagus nerve pathway ( parasympathetic trunk that connects the esophageal plexus to the medulla oblongata, end to end, gut to brain respectively) is a critical communication trunk that carry gut signal, including the microbiota signals to the brain.  Since we have been discussing dark age medical treatments, up until the early 1980’s to inhibit stomach acid production in the stomach to cure peptic ulcers gastroenterologists would cut the vagus nerve.  The latin word Vagus means ‘Wandering’ which also refers to these barbaric physicians who carried out this procedure..’Wandering lumps of ignorance’.

Serotonin manufacture

We already know Serotonin (5-Hydroxytryptamine (5HT)) is manufactured in the gut by Bacterial species Lactobacillus and Bifidobacteria while Enterochromaffin cells (EC), that are found in the colon pick up a reserve of 5HT. This reserve is transported to the mucosa, lumen and circulating blood platelets and in fact to 14 different 5HT receptor sites. 5HT provides signaling stimulus to a cell found in the GI tract called the Interstitial ( space between structures of objects ) cell of Cajal ( named after Santiago Cajal, Spanish pathologist), (ICC) that work as an electrical pacemaker generating electrical slow waves to the smooth muscle making Peristalsis possible. The wave frequencies that occur in the GI Tract are:

Stomach – 3/minute

Duodenum – 11-12/minute

Ileum – 9-10/minute

Colon – 3-4/minute

5HT that is injected into the blood maintains homeostasis control ( Blood clotting), vasodilation ( blood vessel dilation lowering blood pressure regulated by the Autonomic nervous system (Sympathetic branch), pain and nausea perception, and influences bone development. Interestingly, 5HT influences intestinal integrity, since epithelial cells secrete SERT (Serotonin selective Reuptake Transporter) which is also responsible for uptake in the brain. It also has been discovered that approx 2% of the neurons in the myenteric plexus( the major nerve supply to the GI Tract ) is serotonergic, where SERT acts like a sponge removing the 5HT from the interstitial cells and soaking the epithelial cells.

Low Serotonin due to Inflammatory Bowel conditions

Lower serotonin levels are detected when inflammatory conditions like Crohn’s disease ( autoimmune disease where the immune system attacks the GI Tract), and Ulcerative colitis ( autoimmune disease where the immune system attacks the colon ); both conditions are referred to as Irritable bowel diseases. It is known that 5HT is synthesized by the interplay between enterochromaffin cells (EC), the mucosal mast cells, myenteric neurons and 2 different Isoenzymes ( Isozymes or a multiple enzyme complex ) of Tryptophan Hydroxylase ( TPH) that mediate neuronal activity but how it is accomplished is unknown.

ACE (Angiotensin Converting enzyme), GAD (Glutamic acid decarboxylase) and GABA

I want to draw your attention toward 2 enzymes that are related to stress, namely ACE (Angiotensin Converting enzyme) and GAD ( Glutamic acid decarboxylase ) an enzyme responsible for producing GABA ( Gamma aminobutyric acid) which is a crucial inhibitory neurotransmitter in neurons and the beta pancreatic cells. It is also an identified ‘Perp’ in autoimmune disease and Type 1 diabetes.  Angiotensin is responsible for vasoconstriction ( blood vessel constriction) triggered by the Autonomic Nervous system ( Sympathetic branch) to regulate arterial diameters, in order to increase or decrease blood flow to various organs. A normal intelligent function of the body I might add, but of course this action will obviously alter blood pressure. Angiotensin I is a protein produced by the liver and released into the blood. ACE converts Angiotensin I to Angiotensin II for the purpose of blood flow regulation. Since Allopathic medicine is on the ‘warpath’ to keep everybody on the same blood pressure ( because it causes strokes ???) they prescribe ACE inhibitors to lower blood pressure and in the words of Dr Bergeman ‘ to have the audacity to second guess the body’. Furthermore, the other functions of Angiotensin II is Growth induction, cell migration, mitosis of vascular smooth muscle cells, increased synthesis of collagen in fibroblasts, as well as some involvement in myocardium repair process following a myocardial infarction.

Rehydration axis, The Renin-angiotensin-aldosterone system

Stress enzymes, GAD ,ACE and the Angiotensin protein are also related to adrenal stress and Aldosterone ( an adrenal activated hormone that affects blood pressure regulation by signaling the kidney/colon to increase the amount of sodium released in the blood and the amount of potassium released into the urine. In addition, it triggers the uptake of water and sodium into the blood to increase blood volume, and helps in the maintenance of PH and Electrolyte levels. Thus Aldosterone is linked to 2 other hormones Renin and Angiotensin forming the rehydration axis; the Renin-angiotensin-aldosterone system which is activated upon detection of low blood pressure.   This axial system kicks in to regulate plasma sodium concentration and arterial blood pressure …wait, one of the side effects of the ACE inhibitor is hypotension ( low blood pressure ) so the inhibition of the enzyme to produce Angiotensin must result in the collapse of this functional axis. When sympathetic stress is activated, 50% of the stress hormone Adrenaline is sprayed onto the microbiome like fertilizer which enhances the growth of the bacteria included the opportunistic flora. In one research article it described taking a sample of E.Coli from the gut and placing it into 2 Petri dishes and one was sprayed with Adrenaline, then left  for 24 hours. Then the sprayed petri dish was examined and the E.Coli had grown 10,000% faster than the other unsprayed culture.  This experiment shows that stress and its associated hormone can cause microbiota overgrowth and thus gut imbalance.

High stress levels in gnotobiotic mice

There may be an evolutionary reason as well as a biological reason for this inter-communication between gut microbes and the brain, which John Cryan, a neuroscientist at the University of Cork in Ireland hypothesized, in that humans must remain social creatures in order to procreate. His experiments show that the gnotobiotic ( germ free mice ) fail to interact with other mice, and since their immune system and brains are underdeveloped they do not have the same inhibitory characteristics as normal mice with gut flora so they are hyperactive and daring. In Japan 10 years ago mice were restrained in a narrow tube for an a hour, after which their stress hormone levels were measured and found to be higher than normal because of the absence of a gut flora. As soon as one microbial species was added to the gut (Bifidobacterium infantis) stress hormone levels returned to normal.

Microbial regulation of stress hormone secretion

So our microbiome also regulates the secretion of stress hormones, notably these hormones are released by the hypothalamic-pituitary-adrenal axis, i.e the Gut-brain connection. Furthermore, microbiologist Premysl Bercik and gastroenterologist Stephen Collins both at McMaster University Ontario Canada confirmed that by colonising a germ free mouse with the bacteria from another mouse the recipient inherits the donors personality. This is indeed proof of how powerful this gut-brain connection really is, and Psychiatrists want to drug these so-called ‘brain disorders’..it defies reasonable logic. Furthermore, they were also able to recreate Irritable bowel syndrome in mice by the same transplantation process, inducing in the recipient,constipation, diarrhea, pain and low-grade inflammation. The mice also developed leaky intestines, an activated immune systems and the production of pro-inflammatory metabolites that caused many known nervous system effects including anxious behavior.

Conclusive remarks

Having explored these types of autoimmune conditions I am sure you appreciate the common thread that runs through all of them and indeed all autoimmune conditions, in that the immune system is in chaos and dysfunctional caused by a dysfunctional gut, which in turn is triggered by an environmental signal such as stress.

 

References/Acknowledgments :

    1. The role of Ileocolonoscopy in IBD Rodrigo Catano Liano 2010 Scielo Columbia
    2. Microbial host interaction in IBD: Implications for Pathogenesis & Therapy  Sortor, Muehlbauer 3007 NCB1
    3. Wireless capsule endoscopy vs ileocolonoscopy for the diagnosis of Crohn’s disease : a prospective study 2006 A.Bourreille et al NCBI
    4. Crohn’s disease: a clinical update Ha,Kahlil 2015 NCBI
    5. Research Uncovers Bacteria Linking Crohn’s Disease to Arthritis Feb 2017 Weill Cornell Medicine
    6. CBS News Features New Breakthrough Crohn’s Disease Treatment With IV Ketamine By Dr. Ashraf Hanna May 2017 Cision PR Newswire
    7. Microbiome and disease Part 1 & 2, Microbiome and the Gut Brain Barrier articles Eric Malouin 2017, extremehealthacademy.com
    8. The Mind-Gut connection book 2016 Emeran Mayer MD
    9. Epigenetics book 2014 Dr Joel Wallach, Dr Ma Lan,Dr Gerhard Schrauzer
    10. Overcoming Crohn’s disease & Colitis broadcast 119 2016  Dr Pompa Cellular Healing TV
    11. Crohn’s and Colitis Canada website

My name is Eric Malouin

In terms of my heritage I am not a thoroughbred, I am half English from England and half French Canadian from Quebec. Having spent the last 10 years in Medical research I thought that it was time to share my passion for true health to anybody interested in maintaining health without using conventional medicine. Once in the distant past I lived off conventional grocery shelves until you visit the man in the white coat and then a light shines through the darkness that you had not realized you were in… I was in..the twilight zone….I cured my own problems using natural methods, although they were not a big deal since I have always exercised..jogging every morning and tennis 12 hours/week, swimming but I was eating a lot of devil food that was causing my body to become unbalanced..an easy fix..reprogrammed my taste buds and gave the food back to the devil…lol

I hope you enjoy the articles……